Skin Innovation 

Cell-Penetrating Peptide Delivery Platform

 Overcoming the Limitations of Existing Growth Factor Procedures

Unique Revolutionary Ingredients

Stability optimized for skin formulations


A Complex Formula with 18 Growth Factors Delivers Astonishing Synergy to Safely and 

Effectively Improve Signs of Aging, from Deep Wrinkles to Expression Lines.




Building Technological Advantage with Proprietary Innovations

At Bioplus, we are committed to advancing sustainable, cell-based regenerative medicine. We have pioneered research into innovative mechanisms that effectively deliver growth factors directly into the body, offering a new approach to promoting cellular rejuvenation and repair.

BIOPLUS CO., LTD

205%
maximum
absorption
205%
maximum
absorption
Deeply Penetrating into the Skin

BMTS (Bio-Material Transdermal System): Delivers active ingredients deeper into the skin, maximizing their effect and boosting skin regeneration.


660%
maximum durability
660%
maximum durability
Longer-lasting

AUT (Anti-Ubiquitination Technology): Extends the active ingredients' half-life, keeping them effective for a longer time.

Ref. Data on file BioPlus


Technology Certification Status

Transdermal absorption significantly enhanced through a superior penetration system

25

AUT Registration

6

AUT Application

12

BMTS Registration

3

BMTS Application
How Growth FactorS work

With Shine Plus Aura’s multi-phase delivery system, growth factors don’t just reach the skin — they work with precision, purpose, and power to transform it from within.


Step 1. Penetration 

Enhanced penetration without compromising skin comfort.

Our proprietary AUT technology facilitates the initial delivery of growth factors deep into the skin layers.


Step 2. Retention

Sustained presence for long-lasting effects

BMTS ensures that the delivered actives stay in place where the skin needs them most.


Step 3. Activation

Skin-Regenerative Response

Once growth factors are optimally positioned, they begin to interact with skin cells to support repair, collagen synthesis, and barrier restoration.




Watch the Video!

Witness how growth factors penetrate, stay, and activate within the skin, 

brought to life through 3D visualization. Experience the science behind the transformation.


Skin-Deep? We Go Deeper!

Intelligent Absorption. Targeted Transformation.

Ref. Data on file BioPlus


Stay luminous, longer!

Enduring care. Unfading results.

Ref. Data on file BioPlus


See the Difference








Comparison of general growth factors








Shine Plus AURA’s Growth factors 

Ref. Data on file BioPlus

Shine+ AURA magazine

Dive deeper into beauty — visit our blog for expert tips, science-backed insights, and radiant inspiration. 

Why Dermatologists Trust Growth Factors in Aesthetic Skincare




Find out why growth factors are trusted by skin experts in professional cosmetic care.

In aesthetic medicine, every ingredient matters—and few have changed the field quite like growth factors.


The Role of Growth Factors in Dermatology


Originally studied for their role in wound healing, growth factors have proven to be one of the most effective tools for supporting skin regeneration and collagen remodeling. Dermatologists and cosmetic professionals value these proteins for their ability to promote tissue repair and maintain skin homeostasis.



Scientific Evidence of Effectiveness


Growth factors such as EGF (epidermal growth factor), TGF-β (transforming growth factor-beta), and PDGF (platelet-derived growth factor) are commonly studied for their effects on skin firmness, elasticity, and wound healing. Numerous double-blind, placebo-controlled studies have demonstrated their efficacy in reducing fine lines, tightening the skin, and accelerating recovery after procedures.



Shine Plus Aura’s Professional Commitment


Shine Plus Aura delivers growth factor technology in a clinically optimized format. Our professional medical line is designed for use alongside aesthetic treatments including:

- Microneedling

- Radiofrequency

- Mesotherapy

- Fractional laser

This synergy enhances treatment outcomes while minimizing recovery time.


Why Professionals Trust Our Formulas


We work closely with dermatologists, pharmacologists, and aesthetic nurses to ensure our products are backed by research and safe for professional use. With stable formulations, precise dosing, and clear ingredient transparency, Shine Plus Aura stands out in the rapidly evolving world of cosmetic dermatology.


 Testimonials from the Field


Clinical partners consistently report patient satisfaction with Shine Plus Aura protocols. Faster healing, visible skin tone improvement, and reduced post-treatment inflammation are among the most cited benefits.


Whether used as part of a routine regimen or following an advanced aesthetic procedure, growth factor-based care remains a trusted pillar in dermatology.


#dermatologistrecommendedskincare #clinicalskincaregrowthfactors #aestheticskinrepair #ShinePlusAura





Treat Multiple Skin Concerns with Shine Plus Aura